abstract：:Background and Purpose- Multifaceted quality improvement interventions of stroke care have been shown to improve hospital personnel adherence to evidence-based performance measures and subsequent stroke outcomes. This study aimed to evaluate the cost-effectiveness of a multifaceted quality improvement intervention for...

journal_title：Stroke

authors： Pan Y,Zhang L,Li Z,Meng X,Wang Y,Li H,Liu L,Wang Y

更新日期：2020-04-01 00:00:00

abstract：:Background and Purpose- We aimed to compare outcomes of ischemic stroke patients with nonvalvular atrial fibrillation between earlier and later initiation of direct oral anticoagulants (DOACs) after stroke onset. Methods- From data for 1192 nonvalvular atrial fibrillation patients with acute ischemic stroke or transie...

journal_title：Stroke

authors： Mizoguchi T,Tanaka K,Toyoda K,Yoshimura S,Itabashi R,Takagi M,Todo K,Shiozawa M,Yagita Y,Yoshimoto T,Terasaki T,Yamagami H,Takizawa S,Inoue M,Kamiyama K,Ihara M,Okada Y,Kitazono T,Koga M,SAMURAI Study Investigators.

更新日期：2020-03-01 00:00:00

abstract：:Background and Purpose- Patients with intracerebral hemorrhage (ICH) and atrial fibrillation (AF) are at risk for ischemic events. While risk calculators (CHA2DS2-VASc and HAS-BLED) have been validated to assess risk for ischemic stroke and major bleeding in AF patients, decisions about anticoagulation must consider t...

journal_title：Stroke

authors： Stanton RJ,Eckman MH,Woo D,Moomaw CJ,Haverbusch M,Flaherty ML,Kleindorfer DO

更新日期：2020-03-01 00:00:00

abstract：:Background and Purpose- Enhancement of erythrophagocytosis by macrophages in a timely manner can limit the toxic effects of erythrocyte metabolites and promote brain recovery after intracerebral hemorrhage (ICH). In the current study, we investigated the therapeutic effect of retinoid X receptor agonist, bexarotene, i...

journal_title：Stroke

authors： Chang CF,Massey J,Osherov A,Angenendt da Costa LH,Sansing LH

更新日期：2020-02-01 00:00:00

abstract：:Background and Purpose- The purpose of this study was to conduct a meta-analysis of CVOTs (cardiovascular outcome trials) to evaluate the effect of glucagon-like peptide-1 receptor agonists therapy in reducing the risk of stroke in patients with type 2 diabetes mellitus. Methods- PubMed and other electronic sources we...

journal_title：Stroke

authors： Bellastella G,Maiorino MI,Longo M,Scappaticcio L,Chiodini P,Esposito K,Giugliano D

更新日期：2020-02-01 00:00:00

abstract：:Background and Purpose- The CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) demonstrated equivalent composite outcomes between carotid endarterectomy (CEA) and carotid artery stenting (CAS) for treating carotid stenosis. We investigated nationwide trends in these procedures and associated peripr...

journal_title：Stroke

authors： Cole TS,Mezher AW,Catapano JS,Godzik J,Baranoski JF,Nakaji P,Albuquerque FC,Lawton MT,Little AS,Ducruet AF

更新日期：2020-02-01 00:00:00

abstract：:Background and Purpose- Information on what effect disability before stroke can have on stroke outcome is lacking. We assessed prestroke disability in relation to poststroke hospital outcome. Methods- Analysis of prospectively collected data from the Sentinel Stroke National Audit Programme. A total of 1656 men (mean ...

journal_title：Stroke

authors： Han TS,Fry CH,Gulli G,Affley B,Robin J,Irvin-Sellers M,Fluck D,Kakar P,Sharma S,Sharma P

更新日期：2020-02-01 00:00:00

abstract：:Background and Purpose- The aim of the present study was to evaluate the relationship between normal-appearing white matter (NAWM) integrity and postischemic stroke recovery in 4 main domains including cognition, mood, gait, and dependency. Methods- A prospective study was conducted, including patients diagnosed for a...

journal_title：Stroke

authors： Sagnier S,Catheline G,Dilharreguy B,Linck PA,Coupé P,Munsch F,Bigourdan A,Debruxelles S,Poli M,Olindo S,Renou P,Rouanet F,Dousset V,Berthoz S,Tourdias T,Sibon I

更新日期：2020-02-01 00:00:00

abstract：:Background and Purpose- The relationship between infarct dimensions and neurological progression in patients with acute pontine infarctions remains unclear. This study aimed to investigate the morphometric predictive value of magnetic resonance imaging for early neurological deterioration (END) in acute pontine infarc...

journal_title：Stroke

authors： Li H,Dai Y,Wu H,Luo L,Wei L,Zhou L,Lin Y,Wang Q,Lu Z

更新日期：2020-02-01 00:00:00

abstract：:Background and Purpose- Persistent depression after ischemic stroke is common in stroke survivors and may be even higher in family caregivers, but few studies have examined depressive symptom levels and their predictors in patient and caregiver groups simultaneously. Methods- Stroke survivors and their family caregive...

journal_title：Stroke

authors： Roth DL,Haley WE,Sheehan OC,Liu C,Clay OJ,Rhodes JD,Judd SE,Dhamoon M

更新日期：2020-01-01 00:00:00

abstract：:Background and Purpose- Blood pressure (BP) variability may increase the risk of stroke and dementia. It remains inconclusive whether BP variability is associated with cerebral small vessel disease, a common and potentially devastating subclinical disease that contributes significantly to both stroke and dementia. Met...

journal_title：Stroke

authors： Ma Y,Song A,Viswanathan A,Blacker D,Vernooij MW,Hofman A,Papatheodorou S

更新日期：2020-01-01 00:00:00

abstract：:Background and Purpose- To test the hypothesis that covert brain infarcts (CBIs) are more likely to be located in noneloquent brain areas compared with clinical strokes and that CBI etiological subtypes carry a differential risk of vascular events compared with people without CBI. Methods- We used brain magnetic reson...

journal_title：Stroke

authors： Gutierrez J,Gil-Guevara A,Ramaswamy S,DeRosa J,Di Tullio MR,Cheung K,Rundek T,Sacco RL,Wright CB,Elkind MSV

更新日期：2020-01-01 00:00:00

abstract：:Background and Purpose- To identify the specific post-endovascular stroke therapy (EVT) peak systolic blood pressure (SBP) threshold that best discriminates good from bad functional outcomes (a priori hypothesized to be 160 mm Hg), we conducted a prospective, multicenter, cohort study with a prespecified analysis plan...

journal_title：Stroke

authors： Mistry EA,Sucharew H,Mistry AM,Mehta T,Arora N,Starosciak AK,De Los Rios La Rosa F,Siegler JE 3rd,Barnhill NR,Patel K,Assad S,Tarboosh A,Dakay K,Salwi S,Cruz AS,Wagner J,Fortuny E,Bennett A,James RF,Jagadeesan B,S

更新日期：2019-12-01 00:00:00

abstract：:Background and Purpose- Imaging is frequently used to select acute stroke patients for intra-arterial therapy. Quantitative cerebral blood flow can be measured noninvasively with arterial spin labeling magnetic resonance imaging. Cerebral blood flow levels in the contralateral (unaffected) hemisphere may affect capaci...

journal_title：Stroke

authors： Thamm T,Guo J,Rosenberg J,Liang T,Marks MP,Christensen S,Do HM,Kemp SM,Adair E,Eyngorn I,Mlynash M,Jovin TG,Keogh BP,Chen HJ,Lansberg MG,Albers GW,Zaharchuk G

更新日期：2019-12-01 00:00:00

abstract：:Background and Purpose- Despite evidence to support the prescription of antihypertensive medications before hospital discharge to promote medication adherence and prevent recurrent events, many patients with stroke miss out on these medications at discharge. We aimed to examine patient, clinical, and system-level diff...

journal_title：Stroke

authors： Dalli LL,Kim J,Thrift AG,Andrew NE,Lannin NA,Anderson CS,Grimley R,Katzenellenbogen JM,Boyd J,Lindley RI,Pollack M,Jude M,Durairaj R,Shah D,Cadilhac DA,Kilkenny MF

更新日期：2019-12-01 00:00:00

abstract：:Background and Purpose- More intensive secondary prevention with newer drugs may be cost-effective in patients with coronary artery disease (CAD). Whether some subgroups of patients who had a transient ischemic attack (TIA) or ischemic stroke, but no prior CAD are at similar high risk of myocardial infarction as those...

journal_title：Stroke

authors： Boulanger M,Li L,Lyons S,Lovett NG,Kubiak MM,Silver L,Touzé E,Rothwell PM

更新日期：2019-12-01 00:00:00

abstract：:Background and Purpose- Stroke and Alzheimer disease are 2 major causes of neurological disability in aged people and shared overlapping predictors. In recent prospective studies, high Lp(a) [lipoprotein(a)] level is associated with high risk of stroke but low risk of Alzheimer disease. Whether this reflects a causal ...

journal_title：Stroke

authors： Pan Y,Li H,Wang Y,Meng X,Wang Y

更新日期：2019-12-01 00:00:00

abstract：:Background and Purpose- Knowledge of the use of secondary preventive medication in young adults is limited. We studied the use of statins and its association with subsequent vascular events in young adults with ischemic stroke-a patient group with a known low burden of atherosclerosis. Methods- The study population in...

journal_title：Stroke

authors： van Dongen MME,Aarnio K,Martinez-Majander N,Pirinen J,Sinisalo J,Lehto M,Kaste M,Tatlisumak T,de Leeuw FE,Putaala J

更新日期：2019-12-01 00:00:00

abstract：:Background and Purpose- Perihemorrhagic edema (PHE) is associated with poor outcome after intracerebral hemorrhage (ICH). Infiltration of immune cells is considered a major contributor of PHE. Recent studies suggest that immunomodulation via S1PR (sphingosine-1-phosphate receptor) modulators improve outcome in ICH. Si...

journal_title：Stroke

authors： Bobinger T,Manaenko A,Burkardt P,Beuscher V,Sprügel MI,Roeder SS,Bäuerle T,Seyler L,Nagel AM,Linker RA,Engelhorn T,Dörfler A,Horsten SV,Schwab S,Huttner HB

更新日期：2019-11-01 00:00:00

abstract：:Background and Purpose- Delirium is a common and serious complication of acute illness. We describe delirium occurrence in an unselected, acute stroke population. Methods- We collected data from consecutive stroke admissions. We performed comprehensive cognitive assessment within the first week including Diagnostic St...

journal_title：Stroke

authors： Shaw R,Drozdowska B,Taylor-Rowan M,Elliott E,Cuthbertson G,Stott DJ,Quinn TJ

更新日期：2019-11-01 00:00:00

abstract：:Background and Purpose- The GLX (glycocalyx) is a protein/polysaccharide meshwork at the cellular surface. Consisting largely of glycosaminoglycans and proteoglycans, the GLX can shed in response to stress. In this study, we assay 11 components of the GLX in plasma from patients with ischemic stroke from a longitudina...

journal_title：Stroke

authors： DellaValle B,Hasseldam H,Johansen FF,Iversen HK,Rungby J,Hempel C

更新日期：2019-10-01 00:00:00

abstract：:Background and Purpose- Finding adequate control tissue for intracranial aneurysm (IA) pathophysiological studies, including gene expression studies, can be challenging. We compared gene expression profiles of superficial temporal, cortical, and circle of Willis (CoW) arteries and IA in search of the most optimal cont...

journal_title：Stroke

authors： Laarman MD,Kleinloog R,Bakker MK,Rinkel GJE,Bakkers J,Ruigrok YM

更新日期：2019-10-01 00:00:00

abstract：:Background and Purpose- Depression and anxiety are common after stroke/transient ischemic attack (TIA). These conditions are associated with poor functional outcome and worse quality of life. However, few studies have explored predictors of poststroke risk of generalized anxiety, especially in patients without comorbi...

journal_title：Stroke

authors： Kapoor A,Si K,Yu AYX,Lanctot KL,Herrmann N,Murray BJ,Swartz RH

更新日期：2019-09-01 00:00:00

abstract：:Background and Purpose- Hypertrophic cardiomyopathy patients with atrial fibrillation are at increased risk of stroke, and anticoagulation is strongly recommended. However, limited data are available regarding the safety and effectiveness of non-vitamin K antagonist oral anticoagulants (NOACs) for primary prevention o...

journal_title：Stroke

authors： Lee HJ,Kim HK,Jung JH,Han KD,Lee H,Park JB,Kim HM,Kim YJ,Ommen SR

更新日期：2019-09-01 00:00:00

abstract：:Background and Purpose- Stroke is the most frequent severe clinical event in patients with Fabry disease. We aimed to evaluate the cerebral magnetic resonance imaging findings of patients with Fabry disease and assess their association with future stroke risk after enzyme replacement therapy (ERT) induction. Methods- ...

journal_title：Stroke

authors： Yagita Y,Sakai N,Miwa K,Ohara N,Tanaka M,Sakaguchi M,Kitagawa K,Mochizuki H

更新日期：2019-09-01 00:00:00

abstract：:Background and Purpose- Lacunar strokes are subcortical infarcts with small size and high disability rates, largely due to injury of the corticospinal tract in the internal capsule (IC). Current rodent models of lacunar infarcts are created based on stereotactic coordinates. We tested the hypothesis that better unders...

journal_title：Stroke

authors： Wen TC,Sindhurakar A,Ramirez VC,Park H,Gupta D,Carmel JB

更新日期：2019-09-01 00:00:00

abstract：:Background and Purpose- In this era of endovascular therapy (EVT) with early, complete recanalization and reperfusion, we have observed an even more rapid apparent diffusion coefficient (ADC) normalization within the acute ischemic lesion compared with the natural history or IV-tPA-treated patient. In this study, we a...

journal_title：Stroke

authors： Hsia AW,Luby M,Cullison K,Burton S,Armonda R,Liu AH,Leigh R,Nadareishvili Z,Benson RT,Lynch JK,Latour LL

更新日期：2019-08-01 00:00:00

abstract：:Background and Purpose- The optimal antithrombotic strategy to balance thromboembolic and bleeding events, especially acute stroke, for patients with atrial fibrillation following coronary stenting remains a matter of debate. We conducted a network meta-analysis to identify the antithrombotic regimen associated with t...

journal_title：Stroke

authors： Knijnik L,Rivera M,Blumer V,Cardoso R,Fernandes A,Fernandes G,Ferreira T,Romano JG,Lambrakos LK,Cohen MG

更新日期：2019-08-01 00:00:00

abstract：:Background and Purpose- The impact of a mobile stroke unit (MSU) on access to intraarterial thrombectomy (IAT) is a prespecified BEST-MSU substudy (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit Compared to Standard Management by Emergency Medical Services). On the MSU, IAT decision-making steps, su...

journal_title：Stroke

authors： Czap AL,Grotta JC,Parker SA,Yamal JM,Bowry R,Sheth SA,Rajan SS,Hwang H,Singh N,Bratina P,Bryndziar T,Alexandrov AV,Alexandrov AW,Dusenbury W,Swatzell V,Jones W,Ackerson K,Schimpf B,Wright P,Jagolino-Cole AL

更新日期：2019-07-01 00:00:00

abstract：:Background and Purpose- Mobile Stroke Units (MSUs) provide innovative prehospital stroke care but their 24/7 operation has not been studied. Our study investigates 24/7 MSU diurnal variations related to transport frequency, patient characteristics, and stroke treatments. Methods- We compared transportation frequency, ...

journal_title：Stroke

authors： Zaidat OO,Changal KH,Sultan-Qurraie A,de Havenon A,Calderon VJ,Goins-Whitmore J,Patterson MS,Lin E

更新日期：2019-07-01 00:00:00

abstract：:Background and Purpose- Ischemic stroke is one of the leading causes of morbidity and mortality worldwide and a major cause of long-term disability. Recently, long noncoding RNAs have been revealed, which are tightly associated with several human diseases. However, the functions of long noncoding RNAs in ischemic stro...

journal_title：Stroke

authors： Deng Y,Chen D,Wang L,Gao F,Jin B,Lv H,Zhang G,Sun X,Liu L,Mo D,Ma N,Song L,Huo X,Yan T,Miao Z

更新日期：2019-07-01 00:00:00

abstract：:Background and Purpose- High-resolution vessel wall magnetic resonance imaging is a promising technique for assessing wall structures of unruptured intracranial aneurysms (UIAs). However, the relationship between aneurysmal high-resolution vessel wall magnetic resonance imaging features and their histopathologic mecha...

journal_title：Stroke

authors： Quan K,Song J,Yang Z,Wang D,An Q,Huang L,Liu P,Li P,Tian Y,Zhou L,Zhu W

更新日期：2019-06-01 00:00:00

abstract：:Background and Purpose- Given inconclusive studies, it is debated whether clinical and imaging characteristics, as well as functional outcome, differ among patients with intracerebral hemorrhage (ICH) related to vitamin K antagonists (VKA) versus non-vitamin K antagonist (NOAC)-related ICH. Notably, clinical character...

journal_title：Stroke

authors： Gerner ST,Kuramatsu JB,Sembill JA,Sprügel MI,Hagen M,Knappe RU,Endres M,Haeusler KG,Sobesky J,Schurig J,Zweynert S,Bauer M,Vajkoczy P,Ringleb PA,Purrucker JC,Rizos T,Volkmann J,Müllges W,Kraft P,Schubert AL,Erbgut

更新日期：2019-06-01 00:00:00

abstract：:Background and Purpose- Several vascular risk factors are known to be associated with the occurrence of intracranial aneurysms (IAs). Coronary artery calcium (CAC), which reflects the atherosclerotic burden of the coronary arteries, is a known predictor of cardiovascular events and stroke. We investigated the relation...

journal_title：Stroke

authors： Cho BH,Kim JH,Suh SH,Baik SJ,Lee HS,Kim J,Lee KY

更新日期：2019-06-01 00:00:00

abstract：:Background and Purpose- Many patients with acute ischemic stroke are not eligible for thrombolysis or mechanical reperfusion therapies due to contraindications, inaccessible vascular occlusions, late presentation, or large infarct core. Sphenopalatine ganglion (SPG) stimulation to enhance collateral flow and stabilize...

journal_title：Stroke

authors： Bornstein NM,Saver JL,Diener HC,Gorelick PB,Shuaib A,Solberg Y,Devlin T,Leung T,Molina CA,ImpACT-24A Investigators † .,ImpACT-24A Investigators include the Site Principal Investigators, DSMB members, and the Site Co-Investigators lis

更新日期：2019-05-23 00:00:00

abstract：:Background and Purpose- Disturbance of endoplasmic reticulum (ER) Ca2+ homeostasis causes neuronal cell injury in stroke. By contrast, ischemic preconditioning (IPC)-a brief sublethal ischemic episode affording tolerance to a subsequent ischemic insult-restores ER Ca2+ homeostasis. Under physiological conditions, ER c...

journal_title：Stroke

authors： Secondo A,Petrozziello T,Tedeschi V,Boscia F,Vinciguerra A,Ciccone R,Pannaccione A,Molinaro P,Pignataro G,Annunziato L

更新日期：2019-05-01 00:00:00

abstract：:Background and Purpose- Hemispheric stroke studies associating lateropulsion (pusher syndrome) with the location of brain lesions have had mixed results from small, unmatched samples. This study was designed to determine whether lateropulsion localizes to specific brain regions across patients with stroke using a case...

journal_title：Stroke

authors： Babyar SR,Smeragliuolo A,Albazron FM,Putrino D,Reding M,Boes AD

更新日期：2019-05-01 00:00:00

abstract：:Background and Purpose- The diagnosis of transient ischemic attack is challenging. Evidence of acute ischemia on MRI diffusion-weighted imaging is highly variable and confirmed in only about one-third of patients. This study investigated the significance of blood-brain barrier dysfunction (BBBD) mapping in patients wi...

journal_title：Stroke

authors： Serlin Y,Ofer J,Ben-Arie G,Veksler R,Ifergane G,Shelef I,Minuk J,Horev A,Friedman A

更新日期：2019-05-01 00:00:00

abstract：:Background and Purpose- Low ankle-brachial index (ABI) identifies a stroke subgroup with high risk of recurrent stroke, cardiovascular events, and death. However, limited data exist on the relationship between low ABI and stroke in low and middle-income countries. Therefore, we evaluated the prevalence of ABI ≤0.90 (w...

journal_title：Stroke

authors： Abboud H,Monteiro Tavares L,Labreuche J,Arauz A,Bryer A,Lavados PM,Massaro A,Munoz Collazos M,Steg PG,Yamout BI,Vicaut E,Amarenco P

更新日期：2019-04-01 00:00:00

abstract：:Background and Purpose- In acute stroke patients with large vessel occlusion, the goal of intravenous thrombolysis (IVT) is to achieve early recanalization (ER). Apart from occlusion site and thrombus length, predictors of early post-IVT recanalization are poorly known. Better collaterals might also facilitate ER, for...

journal_title：Stroke

authors： Seners P,Roca P,Legrand L,Turc G,Cottier JP,Cho TH,Arquizan C,Bracard S,Ozsancak C,Ben Hassen W,Naggara O,Lion S,Debiais S,Berthezene Y,Costalat V,Richard S,Magni C,Mas JL,Baron JC,Oppenheim C

更新日期：2019-04-01 00:00:00